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Bong-Kiun Kaang

Professor

He is a professor of neuroscience in the Department of Biological Sciences of Seoul National University. He is a Fellow of the Korean Academy of Science and Technology.

Kaang’s studies have mainly focused on the molecular mechanisms of learning and memory. In his Ph.D. course, he developed the microinjection-based gene transfer method for Aplysia neurons. This technology opened up a new era of molecular studies on the memory mechanisms in Aplysia, as well as of functional studies of receptors, signaling molecules, and ion channels, which play key roles in neuronal functions. He revealed that serotonin-induced transcription requires the protein kinase-A-mediated phosphorylation of the cAMP-response element-binding protein(CREB). Moreover, he found that multiple pulses of serotonin stimulate gene expression that is mediated by the cAMP-response element(CRE).

He continued to study Aplysia when he set up his own laboratory in Korea – KaangLab Neurobiology. He started by establishing an expressed sequence tag database and transcriptome analyses of Aplysia.

In parallel with these studies in Aplysia, Kaang has expanded his research field to more complex mammalian models. Combining molecular, electrophysiological, and behavioral experimental tools, he began to explore the mechanisms of learning and memory in mice.